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Bacterial Uropathogens in Urinary Tract Infection and Antibiotic Susceptibility Pattern in Riyadh Hospital, Saudi Arabia

Background: Urinary tract infection (UTI) is one of the commonest infections encountered by clinicians and despite the widespread availability of antimicrobial agents. UTI has become difficult to treat because of appearance of pathogens with increasing resistance to antimicrobial agents. The aim and objectives of this study were to determine the etiological Bacterial pathogens of the UTI and to determine the antibiotic sensitivity pattern of pathogens isolated. Results: The present study was carried out from the Central Laboratory of Riyadh Hospital in Saudi Arabia from January 2015 to Jun 2015.Total 116 urine samples were tested bacteriologically and for antibiotic susceptibility using standard procedures. This study describes the relationships between sex, isolated bacterial agents and antibiotic resistance of UTIs. Out of 116 samples of out patients, urinary tract infection (UTI), of these 70(60.35%) belonged to female and 46(39.66%) samples belonged to male patients, while adult patients included (22.41%) of female as well as male patients with the same percentage. It was found that old adult women have a higher prevalence of UTI than men. Escherichia coli was the most common isolate (78.45%) followed by Klebsiella pneumoniae (21.56 %) amongst the gram-negative bacilli. Also, the results showed that, E. coli occurred more frequently in women (50%) than in men (28.45%). All isolates of E. coli and K. pneumoniae were high susceptible to Meropenem, Imipenem, Colistin, Ertapenem and Amikacin. Conclusions: This study showed that E. coli isolates were the predominant pathogens and showed increasing resistance pattern to the commonly prescribed drugs in private practice that in turn leaves the clinicians with very few alternative options of drugs for the treatment of UTIs.


Samiah HS Al-Mijalli

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